Summary The biophysical limitations of existing optogenetic tools restrict the scale, speed, and precision of neural control. Using structure-guided mutagenesis, we have engineered high-potency opsins
Summary Wavefront-controlled light focusing through step-index multimode optical fibers (MMFs) enables minimally invasive endoscopic imaging of biological tissue. However, the spatially variant point spread function
Summary We present two distinct, complementary methods for improving axial resolution in three-dimensional structured illumination microscopy (3D SIM) with minimal or no modification to the
Summary The hippocampus is crucial for spatial navigation, spatial memory, and episodic memory formation. Hippocampal place cells exhibit spatially selective activity within an environment and
Summary Adaptive optics methods have long been used to perform complex light shaping at the output of a multimode fiber (MMF), with the specific aimofcontrolling
Summary The integration of plasmonic structures with step-index optical fibers is gaining traction for both fundamental research and practical applications. However, the challenge lies in
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